Fischer W, Michaelis B
Acta Biol Med Ger. 1981;40(3):299-307.
The slowly adapting stretch receptor neuron exhibits a marked spike adaptation. In the present paper the dependence of the adaptation time constants and other parameters from the stimulus intensity or the stationary discharge frequency was investigated. In general, the adaptation in response to an intracellular current step is sufficiently approximated by the sum of two exponential terms. A transformation of the parameters measured to a feed back subsystem, which describes the effect of the ionic pump, was performed, too. Proceeding from these data, a generalizing conclusion is that the time constants decrease nearly hyperbolically with increasing stationary impulse frequency. This results in a nearly constant product of carrier frequency and adequate time constant. With regard to the degree of adaptation a marked saturation characteristic appears. In qualitative terms, these effects have to be explained mainly by the properties of the ionic pump and its dependence on the concrete in concentrations.
慢适应性牵张感受器神经元表现出明显的锋电位适应。在本文中，研究了适应时间常数和其他参数与刺激强度或静息放电频率的依赖性。一般来说，对细胞内电流阶跃的响应中的适应可以用两个指数项之和充分近似。还对测量的参数进行了转换，转换到一个描述离子泵作用的反馈子系统。从这些数据出发，一个概括性的结论是，时间常数随着静息冲动频率的增加几乎呈双曲线下降。这导致载波频率与适当时间常数的乘积几乎恒定。关于适应程度，出现了明显的饱和特性。定性地说，这些效应主要必须由离子泵的特性及其对具体离子浓度的依赖性来解释。
