Benjaminsen E
Acta Vet Scand. 1981;22(2):189-97. doi: 10.1186/BF03547508.
The effect of prolactin suppression during lactation was studied in 6 sows nursing 5–10 piglets. In order to inhibit prolactin secretion a dopamin agonist (bromocriptine, Parlodel® “Sandoz”) was given per os from about 4 weeks after parturition until weaning 9–17 days later. Plasma prolactin and plasma progesterone were determined by radioimmunoassays. In all animals plasma prolactin was suppressed during the bromocriptine treatment. Two sows resumed ovarian activity during treatment as indicated by elevated plasma progesterone, probably as a result of the low plasma prolactin levels. The results suggest that the elevated plasma prolactin levels during lactation is one of the factors responsible for lactational an oestrus in the sow.
对6头哺乳5至10头仔猪的母猪,研究了泌乳期抑制催乳素的效果。为抑制催乳素分泌,从分娩后约4周起至9至17天后断奶,经口给予多巴胺激动剂(溴隐亭,“山德士” Parlodel®)。采用放射免疫分析法测定血浆催乳素和血浆孕酮。在溴隐亭治疗期间,所有动物的血浆催乳素均受到抑制。两头母猪在治疗期间恢复了卵巢活动,血浆孕酮升高表明了这一点,这可能是血浆催乳素水平低的结果。结果表明,泌乳期血浆催乳素水平升高是母猪泌乳期不发情的原因之一。