Ruokonen J
Allergol Immunopathol (Madr). 1981 Jul-Aug;9(4):281-8.
A short summary of the literature about the cytotoxic leucocyte test was presented. The results of 1824 CLTs involving 23 food allergens were analyzed. Of the foods tested malt, orange, rye, milk, corn, tomato, oats, wheat, brewers yeast and rice were the ten foods giving a reaction most often in the CLT. Except for minor differences the foods were the same as earlier reported to cause reactions most frequently. Age was found to influence the results of the CLT as cow milk caused reactions most frequently with children and while malt with adults. In 92.1% of the tests there was at least one reaction which means that the CLT is quite sensitive. Thus the CLT seems to be mainly useful for the screening of foods suspected to cause symptoms before planning elimination and provocation trials for the diagnosis of food allergy.
本文对细胞毒性白细胞试验的相关文献进行了简要总结。分析了涉及23种食物过敏原的1824次细胞毒性白细胞试验结果。在测试的食物中，麦芽、橙子、黑麦、牛奶、玉米、番茄、燕麦、小麦、啤酒酵母和大米是在细胞毒性白细胞试验中最常引发反应的十种食物。除了细微差异外，这些食物与之前报道的最常引发反应的食物相同。研究发现年龄会影响细胞毒性白细胞试验结果，牛奶在儿童中最常引发反应，而麦芽在成人中最常引发反应。在92.1%的试验中至少出现了一种反应，这意味着细胞毒性白细胞试验相当敏感。因此，细胞毒性白细胞试验似乎主要有助于在计划进行排除和激发试验以诊断食物过敏之前，对疑似引发症状的食物进行筛查。
