Boeckman C R, Stone R, Schueller K
Am J Surg. 1981 Nov;142(5):567-8. doi: 10.1016/0002-9610(81)90427-x.
Forty-one children with Crohn's disease were seen over a 10 year period. Fifty percent of these patients were diagnosed at ages 13 to 16 years. The colon and small bowel were involved in half of the patients. Twenty-six patients required surgery for resection of bowel or diversionary procedures. Sixty percent of the patients with small bowel disease alone responded to medical therapy. We have been unable to document that growth failure can be predictably reversed by surgery. There were no deaths in this series and no patient was lost to follow-up. At present, only one patient is unable to perform the full-time activities of daily living. The longest period of follow-up is 10 years.
在10年期间共诊治了41例克罗恩病患儿。其中50%的患者在13至16岁时被诊断。一半患者的结肠和小肠均受累。26例患者需要接受肠切除手术或改道手术。仅患有小肠疾病的患者中，60%对药物治疗有反应。我们无法证明手术能够可预测地逆转生长发育迟缓。该系列中无死亡病例，也没有患者失访。目前，只有1例患者无法进行日常生活中的全职活动。最长随访期为10年。
