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阴道分娩的硬膜外间隙阻滞镇痛差异。关于其对分娩进程和分娩方式影响的随机研究(作者译)

[Differential peridural analgesia for vaginal delivery. A randomised study of its influence on the progress and mode of delivery (author's transl)].

作者信息

Sprotte G, Rietbrock I, Lehmann V, Roebke A

出版信息

Anaesthesist. 1981 Oct;30(10):49-57.

PMID:7304900
Abstract

This randomised study of 611 deliveries deals with the side effects of a modified extradural analgesic technique. The modification is based on a flexible reduction of local anaesthetic concentration (bupivacaine) which allows a reliable analgesia without a marked loss of labour sensation and bearing down reflex. Randomisation was achieved by offering this analgesia to the parturients in an alternating 24 hours rhythm. Statistical comparisons were carried out for the following groups of deliveries: 1. for deliveries on both of the two alternating days (Group A). 2. for deliveries with and without extradural analgesia of the peridural days (Group B). - 3. for all deliveries with and without extradural analgesia (Group C). - 4. For deliveries without extradural analgesia on "peridural days" and on "alternating days" (Group D). - The main subjects of investigation were the duration of the two stages of delivery, the dynamics of both the cervical dilation and the movement of the fetal head and the frequency, modes and causes of operative and instrumental deliveries. The safety of the analgesic technique was investigated by evaluating its influence on the status of the newborn and on the maternal regulation of body temperature and circulation. The results were obtained as follows: 1. In the group of parturients who had chosen extradural analgesia several antenatal factors accumulated which evidently had a greater influence on the course of delivery than the analgesic technique itself. - 2. The low concentration of local anaesthetic adapted to the labour pain produced a sufficient analgesia in almost every case. - 3. The duration of both stages of delivery was not altered directly by this technique. An average increase of the duration of the second stage by 116 minutes was due to postponed indications of instrumental and operative deliveries by analgesia. - 4. There was no influence on the overall frequency of operative and instrumental deliveries. Extradural analgesia, however, significantly reduced the frequency of caesarean sections to the same extent as it increased instrumental deliveries from the bottom of the pelvis. - 5. The extradural analgesia had no influence on the status of the newborn. - 6. The regulatory mechanisms of circulation and body temperature were not altered by this dosage of extradural analgesia.

摘要

这项针对611例分娩的随机研究探讨了一种改良硬膜外镇痛技术的副作用。该改良基于灵活降低局部麻醉药浓度(布比卡因),这使得在不显著丧失产痛感觉和向下用力反射的情况下能实现可靠的镇痛效果。通过以24小时交替的节律为产妇提供这种镇痛方法来实现随机分组。对以下几组分娩情况进行了统计比较:1. 两天交替日的分娩(A组)。2. 硬膜外日有和没有硬膜外镇痛的分娩(B组)。3. 所有有和没有硬膜外镇痛的分娩(C组)。4. “硬膜外日”和“交替日”没有硬膜外镇痛的分娩(D组)。主要研究对象是分娩两个阶段的持续时间、宫颈扩张和胎头移动的动态情况以及手术助产和器械助产分娩的频率、方式和原因。通过评估其对新生儿状况以及产妇体温和循环调节的影响来研究镇痛技术的安全性。结果如下:1. 在选择硬膜外镇痛的产妇组中,几种产前因素聚集在一起,显然这些因素对分娩过程的影响比镇痛技术本身更大。2. 适应产痛的低浓度局部麻醉药几乎在每种情况下都产生了足够的镇痛效果。3. 该技术并未直接改变分娩两个阶段的持续时间。第二产程平均延长116分钟是由于镇痛导致器械助产和手术助产指征延迟。4. 对手术助产和器械助产分娩的总体频率没有影响。然而,硬膜外镇痛显著降低了剖宫产的频率,同时从骨盆底部增加了器械助产分娩的频率。5. 硬膜外镇痛对新生儿状况没有影响。6. 这种剂量的硬膜外镇痛未改变循环和体温的调节机制。

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