Knoche E, Traub E, Dick W
Anaesthesist. 1979 Apr;28(4):36-42.
From 1975 on, continuous epidural analgesia has been administered at the University Department of Anaesthetics in Ulm to women for pain relief during labour. One group of 350 pregnant women received bupivacaine hydrochloride, from 1. 5. 1976 to 30. 4. 1977, another group of 350 women received bupivacaine carbonate during the period from 1. 5. 1977 to 30. 11. 1977. Within these two groups the different effects of both local anaesthetic agents were compared in respect of the course of labour, the indications for epidural analgesia, the practicability of epidural analgesia, complications during labour, the rate of pain relief, the frequency of operative deliveries and the clinical condition of the newborn. The main advantages of bupivacaine carbonate for obstetric analgesia purposes are demonstrated.
自1975年起,乌尔姆大学麻醉学系就开始为分娩期妇女实施连续硬膜外镇痛以缓解疼痛。一组350名孕妇在1976年5月1日至1977年4月30日期间接受盐酸布比卡因,另一组350名妇女在1977年5月1日至1977年11月30日期间接受碳酸布比卡因。在这两组中,就产程、硬膜外镇痛的指征、硬膜外镇痛的可行性、分娩期并发症、疼痛缓解率、手术分娩频率以及新生儿的临床状况,对两种局部麻醉药的不同效果进行了比较。结果显示了碳酸布比卡因用于产科镇痛的主要优势。