Ramirez-Ronda C H, Fuxench-López Z, Nevárez M
Arch Intern Med. 1981 Nov;141(12):1599-603. doi: 10.1001/archinte.141.12.1599.
The oropharyngeal colonization by Staphylococcus aureus and Gram-negative bacilli (GNB) and its duration were studied in 89 house staff officers, with biweekly quantitative cultures for 11 months. Eighty-two episodes of upper respiratory tract infection were documented during the study period. The oropharyngeal colonization during illness-free periods ranged from 12% to 18% for GNB and from 5% to 14% for S aureus. During an episode of upper respiratory tract infection, the oropharyngeal colonization of GNB increased to 60%; S aureus colonization increased to 43%. The colonization with both GNB and S aureus was transient and lasted for approximately two weeks. The increased colonization by S aureus and GNB during a viral respiratory tract infection may be a factor contributing to the increased risk of pneumonia in patients with this condition.
对89名住院医师的口咽金黄色葡萄球菌和革兰氏阴性杆菌（GNB）定植情况及其持续时间进行了研究，每两周进行一次定量培养，为期11个月。研究期间记录到82例上呼吸道感染发作。在无病期间，GNB的口咽定植率为12%至18%，金黄色葡萄球菌为5%至14%。在上呼吸道感染发作期间，GNB的口咽定植率增至60%；金黄色葡萄球菌定植率增至43%。GNB和金黄色葡萄球菌的定植都是短暂的，持续约两周。病毒呼吸道感染期间金黄色葡萄球菌和GNB定植增加可能是导致此类患者肺炎风险增加的一个因素。
