Epstein J, Tuazon C U
Arch Intern Med. 1981 Nov;141(12):1697-8.
Lymphadenitis caused by Candida developed in a patient with acute leukemia but there was no other evidence of disseminated infection. He was successfully treated intravenously with only 800 mg of amphotericin B. The presentation of disseminated candidiasis in immunocompromised hosts is discussed. The unusual finding in this case of Candida infection apparently confined to a lymph node was interpreted as a stage of fungal invasion more limited than the widely disseminated disease. The concept of a locally invasive but nondisseminated Candida infection was the basis for giving this patient a low dose of amphotericin B.
一名急性白血病患者发生了由念珠菌引起的淋巴结炎，但无其他播散性感染的证据。仅静脉注射800毫克两性霉素B就成功治愈了他。本文讨论了免疫功能低下宿主中播散性念珠菌病的表现。该病例中念珠菌感染明显局限于一个淋巴结这一不寻常的发现被解释为真菌侵袭阶段比广泛播散性疾病更有限。局部侵袭但非播散性念珠菌感染的概念是给予该患者低剂量两性霉素B的依据。
