Spaan J A, Breuls N P, Laird J D
Basic Res Cardiol. 1981 Sep-Oct;76(5):582-6. doi: 10.1007/BF01908365.
Normally systolic coronary blood flow is almost entirely forward. As perfusion pressure was lowered through the autoregulatory range in open-chest dogs, net systolic back flow appeared at approximately 70 mm Hg. Imposing a series resistance (Rs), which impedes both forward and back flow, abolished this reverse flow and resulted in net forward systolic flow. Thus we conclude that under normal perfusion conditions the pattern of net forward systolic flow contains a substantial reverse flow component.
正常情况下,冠状动脉的收缩期血流几乎完全是向前的。在开胸狗身上,当灌注压在自动调节范围内降低时,大约在70毫米汞柱时出现了收缩期净逆流。施加一个串联阻力(Rs),它会阻碍向前和向后的血流,消除了这种逆流,并导致了收缩期净向前血流。因此我们得出结论,在正常灌注条件下,收缩期净向前血流模式包含相当大的逆流成分。