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柯利犬的视杆-视锥发育异常

Rod-cone dysplasia in the collie.

作者信息

Wolf E D, Vainisi S J, Santos-Anderson R

出版信息

J Am Vet Med Assoc. 1978 Nov 15;173(10):1331-3.

PMID:730609
Abstract

Rod-cone dysplasia in the Collie was studied. Night blindness developed early (6 wk) and progressed to nearly total blindness by 1 year of age. Tapetal hyper-reflectivity, vessel attenuation, and optic nerve pallor were clinically evident by 6 months of age. Electroretinography demonstrated markedly reduced retinal response as early as 16 days of age. The results of selective breedings conformed to a single recessive pattern of inheritance.

摘要

对柯利牧羊犬的视杆-视锥发育不良进行了研究。夜盲症出现较早(6周龄),到1岁时发展为几乎完全失明。6月龄时,临床上明显可见脉络膜反光增强、血管变细和视神经苍白。视网膜电图显示,早在16日龄时视网膜反应就明显降低。选择性繁殖的结果符合单一隐性遗传模式。

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Rod-cone dysplasia in the collie.柯利犬的视杆-视锥发育异常
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Union makes strength: a worldwide collaborative genetic and clinical study to provide a comprehensive survey of RD3 mutations and delineate the associated phenotype.联合力量:一项全球性的合作遗传和临床研究,旨在全面调查 RD3 突变并描绘相关表型。
PLoS One. 2013;8(1):e51622. doi: 10.1371/journal.pone.0051622. Epub 2013 Jan 7.
4
Canine RD3 mutation establishes rod-cone dysplasia type 2 (rcd2) as ortholog of human and murine rd3.犬类RD3突变将2型视锥视杆营养不良(rcd2)确定为人类和小鼠rd3的直系同源物。
Mamm Genome. 2009 Feb;20(2):109-23. doi: 10.1007/s00335-008-9163-4. Epub 2009 Jan 9.
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Clinical electrophysiology in veterinary ophthalmology--the past, present and future.兽医眼科学中的临床电生理学——过去、现在与未来
Doc Ophthalmol. 2002 Jan;104(1):5-16. doi: 10.1023/a:1014463514302.
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Slowly progressive changes of the retina and retinal pigment epithelium in Briard dogs with hereditary retinal dystrophy. A morphological study.患有遗传性视网膜营养不良的伯瑞犬视网膜及视网膜色素上皮的缓慢进行性变化。一项形态学研究。
Doc Ophthalmol. 1994;87(4):337-54. doi: 10.1007/BF01203343.
7
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