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[儿茶酚胺及其拮抗剂对兔牙髓刺激诱发的大脑皮质牙区反应的影响]

[Effect of catecholamines and their antagonists on the responses of the dental areas of the cerebral cortex evoked by dental pulp stimulation in the rabbit].

作者信息

Degtiarev V P, Gromov A N

出版信息

Farmakol Toksikol. 1981 Jul-Aug;44(4):404-6.

PMID:7306305
Abstract

The primary responses of the dental areas of the brain cortex in anesthetized rabbits were recorded to demonstrate that application of the alpha-adrenomimetic noradrenaline and beta-adrenolytic propranolol to the cortex suppressed, while application of the beta-adrenomimetic isadrin and alpha-adrenolytic phentolamine potentiated the electrical responses to nociceptive stimulation of the dental pulp. It was found that phentolamine exerted dissimilar effects.

摘要

记录了麻醉兔大脑皮层牙齿区域的初级反应,以证明向皮层应用α-肾上腺素能激动剂去甲肾上腺素和β-肾上腺素能阻滞剂普萘洛尔会抑制反应,而应用β-肾上腺素能激动剂异他林和α-肾上腺素能阻滞剂酚妥拉明会增强对牙髓伤害性刺激的电反应。发现酚妥拉明产生了不同的作用。

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