[肾上腺素能化合物对牙髓刺激诱发的脑电位的影响]
[Effect of adrenergic compounds on the brain potentials evoked by stimulation of the dental pulp].
作者信息
Shelikhov V N, Degtiarev V P
出版信息
Farmakol Toksikol. 1975 Nov-Dec;38(6):676-9.
PMID:6308
Abstract
Intraventriculare injections have brough evidence that alpha-adrenomimetic norepinephrine and beta-adrenomimetic isopropylnorepinephrine augment in the senso-motor region of the cortex the amplitude of primary responses evoked through a dental pulp stimulation. The alpha-adrenoblocking agents--dihydroergotoxin and phentolamine and the beta-edrenoblocking agent propranolol force down the amplitude of primary responses. The sphere of the drugs action is presumed to be the thalamic nuclei.
摘要
脑室内注射已提供证据表明，α-肾上腺素能的去甲肾上腺素和β-肾上腺素能的异丙去甲肾上腺素可增强在皮层感觉运动区通过牙髓刺激诱发的初级反应的幅度。α-肾上腺素能阻滞剂——双氢麦角毒素和酚妥拉明以及β-肾上腺素能阻滞剂普萘洛尔可降低初级反应的幅度。推测药物的作用部位是丘脑核。
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