豚鼠乳头肌在2,4-二硝基苯酚中毒及恢复过程中的兴奋-收缩偶联：1. 对心脏机械活动的影响。
E-C coupling during poisoning with 2,4-dinitrophenol and recovery in papillary muscle of guinea-pig: 1. Effect on the cardiac mechanical activity.
作者信息
Re G G, Ageno R
出版信息
Boll Soc Ital Biol Sper. 1981 Sep 15;57(17):1789-92.
PMID:7306418
Abstract
The effects of 2.4-Dinitrophenol on the mechanical activity of Guinea-pig papillary muscles were studied. 1 x 10(-4) M DNP initially potentiated the contraction and subsequently suppressed the mechanical activity in about 12 min. During the negative inotropic phase a contracture was developed. All the effects were reversible.
摘要
研究了2,4-二硝基苯酚对豚鼠乳头肌机械活动的影响。1×10⁻⁴M的二硝基苯酚最初增强收缩，随后在约12分钟内抑制机械活动。在负性肌力阶段会出现挛缩。所有这些效应都是可逆的。
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