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Purification and characterization of amino-terminal pro-opiocortin peptides from human pituitary glands.

作者信息

McLean C, Hope J, Salacinski P, Estivariz F, Lowry P J

出版信息

Biosci Rep. 1981 Nov;1(11):843-9. doi: 10.1007/BF01114817.

DOI:10.1007/BF01114817
PMID:7306687
Abstract

Two cystine-containing peptides isolated from human pituitaries were partially sequenced. The peptides are fragments derived from the amino-terminal of pro-opiocortin (NPOC) and have been chemically characterized as NPOC 1-28 (which lacks gamma-MSH) and NPOC 2-59. Their availability enables us to investigate new putative biological roles for the amino-terminal conserved sequence of pro-opiocortin.

摘要

相似文献

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Purification and characterization of amino-terminal pro-opiocortin peptides from human pituitary glands.
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引用本文的文献

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POMC: The Physiological Power of Hormone Processing.POMC:激素加工的生理动力。
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Comparative Effect of ACTH and Related Peptides on Proliferation and Growth of Rat Adrenal Gland.促肾上腺皮质激素(ACTH)及相关肽对大鼠肾上腺增殖和生长的比较作用
Front Endocrinol (Lausanne). 2016 May 9;7:39. doi: 10.3389/fendo.2016.00039. eCollection 2016.
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Peripheral administration of the N-terminal pro-opiomelanocortin fragment 1-28 to Pomc-/- mice reduces food intake and weight but does not affect adrenal growth or corticosterone production.向阿黑皮素原基因敲除(Pomc-/-)小鼠外周给予N端促阿黑皮素原片段1-28可减少食物摄入量和体重,但不影响肾上腺生长或皮质酮生成。
J Endocrinol. 2006 Aug;190(2):515-25. doi: 10.1677/joe.1.06749.