神经生长因子处理后体外培养的大鼠肾上腺髓质嗜铬细胞形成的生长锥超微结构
Ultrastructure of growth cones formed by isolated rat adrenal medullary chromaffin cells in vitro after treatment with nerve growth factor.
作者信息
Millar T J, Unsicker K
出版信息
Brain Res. 1981 Nov;254(4):577-82. doi: 10.1016/0165-3806(81)90025-0.
PMID:7306828
Abstract
Growth cones formed by adrenal chromaffin cells from young postnatal rats cultured in the presence of nerve growth factor (NGF) were studied at an electron microscopic level. These growth cones are similar in many respects to those formed by sympathetic neurons in vitro supporting the view that NGF-treated chromaffin cells may undergo neuronal transdifferentiation.
摘要
在电子显微镜水平上研究了在神经生长因子（NGF）存在下培养的新生大鼠肾上腺嗜铬细胞形成的生长锥。这些生长锥在许多方面与体外培养的交感神经元形成的生长锥相似，这支持了NGF处理的嗜铬细胞可能发生神经元转分化的观点。
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