Nussbaum M, Buchwald R P, Ribner A, Mori K, Litwins J
Cancer. 1981 Dec 15;48(12):2724-8. doi: 10.1002/1097-0142(19811215)48:12<2724::aid-cncr2820481228>3.0.co;2-1.
The first case of anaplastic carcinoma arising in median ectopic thyroid (thyroglossal duct remnants) in an 84-year-old woman is presented. This expands the spectrum of histologic types of thyroid malignancies reported in this location and supports the theory that these carcinomas arise from thyroid rests associated with thyroglossal ducts. The presence of a histologically benign follicular neoplasm adjacent to the carcinoma suggests the possibility that the anaplastic carcinoma resulted from the transformation of an underlying well-differentiated tumor. Some unusual features of this case are discussed as well as the criteria for establishing the diagnosis of carcinoma arising in a thyroglossal duct remnant.
本文报道了一例84岁女性发生于中位异位甲状腺（甲状舌管残余）的间变性癌。这拓宽了该部位报道的甲状腺恶性肿瘤的组织学类型谱，并支持了这些癌起源于与甲状舌管相关的甲状腺残余组织的理论。癌旁存在组织学上良性的滤泡性肿瘤提示间变性癌可能由潜在的高分化肿瘤转变而来。本文讨论了该病例的一些不寻常特征以及甲状舌管残余组织中癌的诊断标准。
