Doerr H W, Hoferer E, Leschhorn V, Nassal J
Dtsch Med Wochenschr. 1981 Nov 13;106(46):1532-5. doi: 10.1055/s-2008-1070548.
Comparative analysis of two Q fever epidemics in Baden-Württemberg demonstrated the following characteristics of this zoo-anthroponosis endemic in southern Germany: 1. affected areas are situated along sheep tracks and natural concentrations of the Dermacentor marginatus. 2. The disease spreads in waves. 3. It causes typical symptoms, particular an intense tension headache, and typical radiographic findings. Men are more commonly and more severely affected than women. Children are not affected despite proven exposure. 4. The CBR antibody titre is a reliable laboratory diagnostic parameter. 5. Epidemiological measures (search for the source of infection, elimination of seropositive sheep, use of disinfectants) reduce the reservoir of the infective agent. 6. The therapeutic drug of choice is doxycyclin.
对巴登-符腾堡州两起Q热疫情的比较分析揭示了德国南部这种人畜共患地方病的以下特征：1. 受影响地区位于沿绵羊踪迹以及边缘革蜱自然聚集区。2. 疾病呈波浪式传播。3. 它会引发典型症状，尤其是剧烈的紧张性头痛以及典型的影像学表现。男性比女性更常且更严重地受到影响。尽管有证据表明儿童接触过病原体，但他们未受感染。4. CBR抗体滴度是可靠的实验室诊断参数。5. 流行病学措施（寻找传染源、清除血清阳性绵羊、使用消毒剂）可减少传染源储存库。6. 首选治疗药物是强力霉素。
