Levine M W, Shefner J M
Exp Brain Res. 1981;44(4):353-61. doi: 10.1007/BF00238828.
We recorded from ganglion cell axons in the optic tracts of self-respiring goldfish, and examined the interaction of rod-effective and cone-effective stimuli within their receptive fields. The summation of influences due to the rod system and the long wavelength sensitive cone system was analyzed by the methods of response-summation and sensitivity-summation. Different spatial relationships between the rod- and cone-effective stimuli allowed examination of distance-dependent effects. Both the response-summation and sensitivity-summation analyses showed a difference in non-linearity between a configuration in which the rod- and cone-effective stimuli were spatially overlapped and a configuration in which they were not. This difference in both analyses demonstrates a distance dependent interaction between the rod and cone systems. Both analyses also showed a difference in non-linearity between a configuration in which the rod-and cone-effective stimuli were nearby (but not overlapped) and one in which they were more distant. This demonstrates that the interaction is not limited to receptors that are immediate neighbors. An estimate of the strength of interaction in each case showed that the differences among the three configurations were relatively slight, indicating a broad spread of the effect. The interaction was found to be relatively powerful; assuming a specific simple model for the interaction mechanism, we found that each system exerts an effect upon the other which accounts for about 1/3 of its signal.
我们记录了自主呼吸金鱼视束中神经节细胞轴突的活动，并研究了其感受野内视杆有效刺激和视锥有效刺激之间的相互作用。通过反应总和法和敏感度总和法分析了视杆系统和长波长敏感视锥系统的影响总和。视杆有效刺激和视锥有效刺激之间不同的空间关系，使得我们能够研究距离依赖性效应。反应总和分析和敏感度总和分析均显示，视杆有效刺激和视锥有效刺激在空间上重叠的配置与不重叠的配置之间，非线性存在差异。这两种分析中的差异都表明视杆系统和视锥系统之间存在距离依赖性相互作用。两种分析还显示，视杆有效刺激和视锥有效刺激相邻（但不重叠）的配置与它们距离更远的配置之间，非线性存在差异。这表明这种相互作用并不局限于紧邻的感受器。对每种情况下相互作用强度的估计表明，三种配置之间的差异相对较小，这表明这种效应的传播范围较广。我们发现这种相互作用相对较强；假设相互作用机制的一个特定简单模型，我们发现每个系统对另一个系统施加的影响约占其信号的1/3。
