Lakin K M, Makarov V A, Bobrova L N, Stepanenko B N, Meleshko K V
Farmakol Toksikol. 1981 Nov-Dec;44(6):692-5.
Fructose diphosphate, fructose monophosphate and inorganic phosphate decrease platelet aggregation. Fructose does not affect the function under study. The most pronounced antiaggregation action is displayed by fructose diphosphate which enhances calcium binding with thrombocytic membranes. The action of fructose diphosphate depends on the time of its presence in the blood channel. Fifteen minutes after injection the substance inhibits the formation of experimental thrombocytic thromboses. After one hour such an effect does not manifest since fructose diphosphate is absent from the blood flow by that time.
果糖二磷酸、果糖一磷酸和无机磷酸盐可降低血小板聚集。果糖不影响所研究的功能。果糖二磷酸表现出最显著的抗聚集作用，它能增强钙与血小板细胞膜的结合。果糖二磷酸的作用取决于其在血流中存在的时间。注射后15分钟，该物质可抑制实验性血小板血栓的形成。1小时后，这种作用不再显现，因为此时血流中已不存在果糖二磷酸。
