Irsigler K, Kritz H, Hagmüller G, Franetzki M, Prestele K, Thurow H, Geisen K
Diabetes. 1981 Dec;30(12):1072-5. doi: 10.2337/diab.30.12.1072.
This is a report of the implantation and first 100-day operation using a remote-controlled programmable insulin infusion device in an insulin-dependent diabetic. To prevent insulin aggregation, a special surface-active polymer developed by Hoechst AG, Frankfurt, was used as an additive. Implantation was completed on April 8, 1981, and good metabolic control was reached immediately and has continued to date (July 1981), with this unit providing the only source of insulin. There have been no hypoglycemic attacks. Patient acceptance is very good. The Siemens unit, PFA 01 (external) and DFA 01 (implanted) has proved reliable and precise.
这是一份关于在一名胰岛素依赖型糖尿病患者中使用遥控可编程胰岛素输注装置进行植入及首个100天手术的报告。为防止胰岛素聚集,使用了由法兰克福的赫斯特股份公司研发的一种特殊表面活性聚合物作为添加剂。植入手术于1981年4月8日完成,术后立即实现了良好的代谢控制,并且一直持续到目前(1981年7月),该装置是胰岛素的唯一来源。未发生低血糖发作。患者接受度非常好。西门子装置,PFA 01(外部)和DFA 01(植入式)已证明可靠且精确。