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[意大利人群HLA - DR抗原样本分析。基因频率与配子关联]

[Analysis of a sample of the Italian population for HLA-DR antigen. Gene frequencies and gametic associations].

作者信息

Olivetti E, Crepaldi T, Borelli I, Richiardi P, Curtoni E S

出版信息

G Batteriol Virol Immunol. 1980 Jul-Dec;73(7-12):190-5.

PMID:7308612
Abstract

A random sample of 177 individuals from the Italian population was typed for eight HLA-DR antigens. Gene frequencies and linkage disequilibria were calculated. The most different frequencies, when compared with other european populations, are those of DR5 and DRw6. Most of the linkage disequilibria observed are the same found in other european populations, but some disequilibria present only in Italian population were also observed.

摘要

从意大利人群中随机抽取177人,对8种HLA - DR抗原进行分型。计算了基因频率和连锁不平衡。与其他欧洲人群相比,差异最大的频率是DR5和DRw6的频率。观察到的大多数连锁不平衡与其他欧洲人群中发现的相同,但也观察到了一些仅在意大利人群中存在的不平衡。

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