意大利大陆地区和撒丁岛的备解素因子B多态性
Properdin factor B polymorphism in continental Italy and Sardinia.
作者信息
Malavasi F, Olivetti E, Milanese C, Carbonara A O
出版信息
Hum Genet. 1981;58(2):209-12. doi: 10.1007/BF00278713.
A sample of healthy unrelated individuals (882 from Continental Italy and Sicily, and 139 from Sardinia) were typed for HLA and Bf polymorphisms. Bf gene frequencies in Continental Italy and Sicily show an intermediate position among European populations, with Lapps on one side and Basques on the other side; while a very peculiar pattern is observed among Sardinians, with an impressive similarity with French Basques and with the highest F1 gene frequency so far observed. The HLA:Bf gametic associations in Italy and Sardinia are also reported, which confirm the different ethnic background of these populations.
对一组健康的无亲缘关系个体（882名来自意大利大陆和西西里岛，139名来自撒丁岛）进行了HLA和Bf多态性分型。意大利大陆和西西里岛的Bf基因频率在欧洲人群中处于中间位置，一侧是拉普人，另一侧是巴斯克人；而在撒丁岛人群中观察到一种非常特殊的模式，与法国巴斯克人有惊人的相似性，且F1基因频率是迄今为止观察到的最高值。还报告了意大利和撒丁岛的HLA:Bf配子关联情况，这证实了这些人群不同的种族背景。
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