Konrad E A, Meister P, Lob G, Kessler M
J Cancer Res Clin Oncol. 1981;101(2):213-7. doi: 10.1007/BF00413315.
Chordomas are malignant tumors with lobulated structure which usually consists of vacuolated physaliferous cells in a mucoid stroma (Enzinger et al. 1969). These cells originate from remnants of the chorda dorsalis. Most chordomas are located either at the end of the vertebral column, i.e., in the sacrococcygeal region or at the base of the skull near the sphenooccipital synchondrosis. More than half of all tumors are located in the sacrococcygeal region. In contrast to most cases of sacrococcygeal chordomas which show a predominant presacral tumor infiltration we report on a patient suffering from a sacrococcygeal chordoma with a retrosacral tumor mass. Here, the presacral tumor infiltration became apparent only much latter. It was nevertheless of great prognostic relevance as tumor infiltration of the urinary bladder lead to lethal septicaemia.
脊索瘤是一种具有分叶状结构的恶性肿瘤，通常由黏液样基质中的空泡状泡状细胞组成（恩津格等人，1969年）。这些细胞起源于脊索的残余部分。大多数脊索瘤位于脊柱末端，即骶尾区域或靠近蝶枕软骨结合处的颅底。所有肿瘤中超过一半位于骶尾区域。与大多数骶尾脊索瘤主要表现为骶前肿瘤浸润不同，我们报告了一例患有骶后肿瘤肿块的骶尾脊索瘤患者。在此病例中，骶前肿瘤浸润直到很久以后才变得明显。然而，由于肿瘤浸润膀胱导致致命的败血症，这具有重要的预后意义。
