Faguer C, Darbois Y, Pathier D, Barrat J, Hervet E
J Gynecol Obstet Biol Reprod (Paris). 1978 Sep;7(6):1097-121.
The authors report 189 case histories of pregnant women who had a neurological disorder, which either existed before the pregnancy or were discovered during the pregnancy. The most frequent aetiological conditions were, epilepsy, psychoses, vascular accidents, tumours and disseminated sclerosis. Pregnancy and neuropathology are an association for which the prognosis as a whole is good and linked to the time in the pregnancy when the neurological condition, whether it is stable or not, is discovered. The combination is absolutely compatible with the normal progress of pregnancy so long as the appropriate treatment is continued during the pregnancy. Cerebral vascular accidents that occur in pregnancy make the prognosis very much worse. In these circumstances neurosurgery may give some hope. This applies also for cerebral tumours, among which pituitary adenoma is becoming more and more frequent. Psychopathies can be a very baffling chapter when they are combined with pregnancy. Finally disseminated sclerosis, once it has been stabilised, is perfectly compatible with the normal outcome for a pregnancy.
作者报告了189例患有神经系统疾病的孕妇病史,这些疾病要么在怀孕前就已存在,要么是在怀孕期间被发现的。最常见的病因是癫痫、精神病、脑血管意外、肿瘤和多发性硬化症。怀孕与神经病理学相关,总体预后良好,且与在孕期发现神经系统疾病(无论其是否稳定)的时间有关。只要在孕期持续进行适当治疗,这种情况与妊娠的正常进展完全相容。孕期发生的脑血管意外会使预后严重恶化。在这种情况下,神经外科手术可能带来一些希望。这同样适用于脑部肿瘤,其中垂体腺瘤越来越常见。当精神病与怀孕并存时,可能会是非常棘手的情况。最后,多发性硬化症一旦病情稳定,与妊娠的正常结局完全相容。