Adler A L, Safai B, Wang Y B, Menendez-Botet C, Good R A
J Dermatol Surg Oncol. 1981 Nov;7(11):911-4. doi: 10.1111/j.1524-4725.1981.tb00188.x.
Basal-cell carcinoma is a malignant epithelial neoplasm that arises from the germinative cells of the epidermis and its appendages. Various causative factors have been implicated in its pathogenesis. In recent years, it has become increasingly apparent that alterations in serum zinc concentration may relate to neoplastic diseases. The objective of this study was to determine whether or not a relationship exists between abnormal serum zinc levels and basal-cell carcinomas. The data indicate that a statistically significant elevation in mean serum zinc levels is associated with this neoplasm. This may, however, not be of clinical significance because of variation in environmental or statistical sampling factors.
基底细胞癌是一种恶性上皮性肿瘤，起源于表皮及其附属器的生发细胞。其发病机制涉及多种致病因素。近年来，越来越明显的是血清锌浓度的改变可能与肿瘤性疾病有关。本研究的目的是确定血清锌水平异常与基底细胞癌之间是否存在关联。数据表明，平均血清锌水平在统计学上显著升高与这种肿瘤有关。然而，由于环境或统计抽样因素的变化，这可能没有临床意义。
