Landaas S, Skrede S, Steen J A
J Clin Chem Clin Biochem. 1981 Oct;19(10):1075-80. doi: 10.1515/cclm.1981.19.10.1075.
A group of 291 children aged 3 weeks to 6 1/2 years was examined at a public maternal and child health center and 260 of them - who were considered to be healthy - were included in the present study. By venipuncture, serum was obtained for the analysis of 6 enzymes, and plasma for the estimation of 9 proteins and for lipid analyses. In different age groups, high levels were found for alkaline phosphatase, lactate dehydrogenase, aspartate aminotransferase, alanine aminotransferase, creatine kinase and gamma-glutamyl transferase. Haptoglobin, alpha 1-antitrypsin, prealbumin and transferrin were present at low concentrations during the first months of life. Transferrin rose later in childhood to above adult levels. Only immunoglobulin M showed a sex difference, with higher values for girls. Breast-fed infants had higher (non-fasting) concentrations of cholesterol and triglycerides than formula-fed babies, and they also had higher levels of aspartate aminotransferase and alanine aminotransferase.
在一家公共母婴健康中心对一组年龄在3周至6岁半的291名儿童进行了检查，其中260名被认为健康的儿童被纳入本研究。通过静脉穿刺获取血清用于分析6种酶，获取血浆用于评估9种蛋白质以及进行脂质分析。在不同年龄组中，发现碱性磷酸酶、乳酸脱氢酶、天冬氨酸转氨酶、丙氨酸转氨酶、肌酸激酶和γ-谷氨酰转移酶水平较高。触珠蛋白、α1-抗胰蛋白酶、前白蛋白和转铁蛋白在生命的最初几个月浓度较低。转铁蛋白在儿童期后期升至高于成人水平。只有免疫球蛋白M存在性别差异，女孩的值更高。母乳喂养的婴儿比配方奶喂养的婴儿具有更高的（非空腹）胆固醇和甘油三酯浓度，并且他们的天冬氨酸转氨酶和丙氨酸转氨酶水平也更高。
