Dominioni L, Dionigi R, Zonta A, Scarponi A, Cincera M, Villa S
Minerva Anestesiol. 1981 Aug;47(8):437-40.
Sequential evaluation of lymphocyte blastogenic response (LBR) to PHA was performed in 10 melanoma patients and in 10 gastric cancer patients undergoing radical operations. Preoperative determinations showed a significant depression of LBR in both patient groups as compared to healthy controls. In patients operated for melanoma the average duration of anesthesia was 101 minutes and in patients who underwent gastric resection it was 192 minutes. In both patient groups a further significant depression of LBR was observed in the early postoperative period; however the LBR returned to preoperative levels more promptly in patients who underwent melanoma excision than in those who underwent gastric resection.
对10例黑色素瘤患者和10例接受根治性手术的胃癌患者进行了对PHA淋巴细胞增殖反应(LBR)的序贯评估。术前测定显示,与健康对照组相比,两组患者的LBR均显著降低。接受黑色素瘤手术的患者平均麻醉时间为101分钟,接受胃切除术的患者平均麻醉时间为192分钟。两组患者术后早期LBR均进一步显著降低;然而,接受黑色素瘤切除术的患者LBR恢复到术前水平的速度比接受胃切除术的患者更快。