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J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):894-9. doi: 10.1136/jnnp.41.10.894.
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本文引用的文献

1
Bilateral studies of cerebral oxygen uptake in young and aged normal subjects and in patients with organic dementia.对年轻和老年正常受试者以及器质性痴呆患者进行的双侧脑氧摄取研究。
J Clin Invest. 1960 Mar;39(3):491-500. doi: 10.1172/JCI104063.
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Cerebral blood flow and oxygen consumption in man.人类的脑血流量与氧耗量。
Physiol Rev. 1959 Apr;39(2):183-238. doi: 10.1152/physrev.1959.39.2.183.
3
Determination of regional cerebral blood flow by inhalation of 133-Xenon.通过吸入133-氙测定局部脑血流量。
Circ Res. 1967 Jan;20(1):124-35. doi: 10.1161/01.res.20.1.124.
4
Regional cerebral blood flow determination by 133-Xe inhalation and external recording: the effect of arterial recirculation.通过吸入133氙并进行外部记录测定局部脑血流量：动脉再循环的影响。
Clin Sci. 1966 Jun;30(3):353-69.
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Regional cerebral blood flow and its regulation in dementia.痴呆症中的局部脑血流量及其调节
Brain. 1971;94(2):273-88. doi: 10.1093/brain/94.2.273.
6
Regional cerebral blood flow in senile and presenile dementia.老年和老年前期痴呆患者的局部脑血流量
Neurology. 1970 Apr;20(4):315-22.
7
Observations on the brains of demented old people.对老年痴呆症患者大脑的观察。
J Neurol Sci. 1970 Sep;11(3):205-42. doi: 10.1016/0022-510x(70)90063-8.
8
Cerebral cortex perfusion rates in dementia.痴呆症中的大脑皮质灌注率
J Neurol Neurosurg Psychiatry. 1970 Aug;33(4):497-500. doi: 10.1136/jnnp.33.4.497.
9
Regional cerebral blood flow in organic dementia with early onset.早发性器质性痴呆的局部脑血流量
Acta Neurol Scand. 1970;46(S43):42-73. doi: 10.1111/j.1600-0404.1970.tb02156.x.
10
Radiological considerations on the aetiological and anatomical background of presenile dementias.关于早老性痴呆病因学和解剖学背景的放射学考量
Acta Neurol Scand. 1970;46(S43):32-41. doi: 10.1111/j.1600-0404.1970.tb02155.x.

痴呆症中局部脑血流量与脑萎缩的相关性。¹³³氙吸入与计算机断层扫描联合研究。

Correlation between regional cerebral blood flow and brain atrophy in dementia. Combined study with 133Xenon inhalation and computerised tomography.

作者信息

Melamed E, Lavy S, Siew F, Bentin S, Cooper G

出版信息

J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):894-9. doi: 10.1136/jnnp.41.10.894.

DOI:10.1136/jnnp.41.10.894
PMID:731237
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC493189/
Abstract

Measurement of the regional cerebral blood flow (rCBF) by the 133Xenon inhalation method and computerised tomography were performed in 25 patients with presenile and senile dementia. Reduction of rCBF and various degrees of ventricular enlargement and cortical sulcal widening were demonstrated in the majority of demented subjects. However, there was no correlation between rCBF values and the severity of ventricular dilatation or cortical atrophy. These findings suggest that loss of brain substance is not an important factor in the reduction of rCBF in dementia.

摘要

对25例早老性和老年性痴呆患者采用氙133吸入法和计算机断层扫描测量局部脑血流量（rCBF）。大多数痴呆患者显示rCBF降低以及不同程度的脑室扩大和脑沟增宽。然而，rCBF值与脑室扩张或皮质萎缩的严重程度之间没有相关性。这些发现表明，脑实质丧失不是痴呆患者rCBF降低的重要因素。