替脑啡君（洪堡D8955）对多发梗死性痴呆患者脑血流量的影响
Effect of tinofedrine (Homburg D8955) on cerebral blood flow in multi-infarct dementia.
作者信息
Merory J, Du Boulay G H, Marshall J, Morris J, Russell R W, Symon L, Thomas D J
出版信息
J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):900-2. doi: 10.1136/jnnp.41.10.900.
Abstract
Tinofedrine, a new derivative of l-norephedrine, was examined for cerebral vasodilator activity in man. Ten patients with reduced cerebral blood flow (CBF) and multi-infarct dementia were given the drug intravenously. Cerebral blood flow increased significantly by 28% from a mean of 43.3 to 55.5 ml/100 g/min.
摘要
替诺非君是左旋去甲麻黄碱的一种新衍生物，已对其在人体中的脑血管舒张活性进行了研究。对10名脑血流量（CBF）减少且患有多发梗死性痴呆的患者进行了静脉给药。脑血流量从平均43.3显著增加28%，至55.5毫升/100克/分钟。
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Effect of tinofedrine (Homburg D8955) on cerebral blood flow in multi-infarct dementia.替脑啡君（洪堡D8955）对多发梗死性痴呆患者脑血流量的影响
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