Miagi M A, Tomberg T A, Kauba T F, Rekand T E, Taba P M
Zh Nevropatol Psikhiatr Im S S Korsakova. 1987;87(1):46-50.
Forty-two patients with acute cerebral infarction were studied for the regional volumetric cerebral blood flow (rVCBF) and central hemodynamics (by integral rheography of the body) before and after the intravenous administration of 10 or 20 mg of cavinton (vinpocetine). It was found that in the absence of changes in the central hemodynamics an increase in the cerebral blood flow was the predominant characteristic, but parodoxical reactions were occasionally observed in the acute period of an extensive hemispherical infarct. The findings of quantitative frequency analysis of the EEG conducted in 40 patients correlated with the results of the study of the blood flow and indicated a more favourable prognosis in brain stem infarction or mild cortical infarction. Treatment of extensive cortical infarction was associated with cases of parodoxical deterioration of brain function which should be taken into account in prescribing cavinton to patients during the acute stage of cerebral infarction.
对42例急性脑梗死患者在静脉注射10毫克或20毫克长春西汀（长春胺乙酯）前后，进行了局部脑血流量（rVCBF）和中心血流动力学（通过全身积分血流图）的研究。结果发现，在中心血流动力学无变化的情况下，脑血流量增加是主要特征，但在广泛半球梗死的急性期偶尔会观察到矛盾反应。对40例患者进行的脑电图定量频率分析结果与血流研究结果相关，表明脑干梗死或轻度皮质梗死的预后更有利。广泛皮质梗死的治疗与脑功能矛盾性恶化的病例相关，在给脑梗死急性期患者开长春西汀处方时应考虑到这一点。
