[Serum immunoglobulin and glycoprotein concentration and mesenchymal reaction in chronic hepatitis and liver cirrhosis].

In the liver needle biopsy specimens of 45 patients with hepatitis chronica persistents, hepatitis chronica aggressiva and cirrhosis of the liver the number of lymphoid cells and fibroblasts, and in the serum of the same patients concentration of IgG, IgA, IgM, alfa-2-macroglobulin and coeuroplasmin was examined. It was established that 1. the number of lymphoid cells and fibroblasts in the liver tissue of patients with hepatitis chronica aggressiva and cirrhosis of the liver increases significantly, 2. there exists a correlation between the number of lymphoid cells and the concentration of IgG, 3. the serum level of the alfa-2-macroglobulin increases parallely with the number of fibroblasts of the liver in hepatitis chronica aggressive and in cirrhosis of the liver.