[Exchange of chloride and bicarbonate at terminal ileum in rabbit: the process active character and physiological sense (author's transl)].

The process of chloride and bicarbonate exchange at the terminal ileum in rabbit and the way it is affected by the alkalinization or acidification of the caecum have been studied. Chloride absorption and bicarbonate secretion takes place at the terminal ileum in rabbit. Administration of DNP (5 X 10(-4) M) in the solution together with an i.v. injection of the same substance (0.11 mg/100 g weight) decreased chloride absorption and, quite markedly, bicarbonate secretion in the ileum. Introduction of an alkaline solution into the caecum reduces bicarbonate secretion in the ileum and simultaneously decreases chloride absorption. Introduction of an acid solution into the caecum produces an increase in ileal bicarbonate secretion, while it reduces chloride absorption.