Schöneberger A
Schweiz Med Wochenschr. 1981 Nov 7;111(45):1678-84.
Among ambulatory patients with rhythm disturbances, selection of those who should be treated is essential. Type and frequency of arrhythmia cannot be considered in isolation from the underlying heart disease. Aims of treatment are improvement of symptoms caused by the arrhythmia and prevention of sudden death. Except for atrial fibrillation in the WPW-syndrome, supraventricular arrhythmias are most frequently treated because of their hemodynamic consequences. Frequent complex premature ventricular beats may be an indication for antiarrhythmic therapy in certain patients with coronary heart disease, since this rhythm disturbance appears to increase the risk of sudden death in this setting. Similarly, premature ventricular beats may have prognostic significance for subsets of patients with hypertrophic cardiomyopathy, mitral valve prolapse and long Q-T syndrome. In general, however, only a small percentage of all ambulatory patients with arrhythmias needs to be treated.
在患有节律紊乱的门诊患者中,选择合适的治疗对象至关重要。心律失常的类型和发作频率不能脱离潜在的心脏病单独考虑。治疗目标是改善心律失常引起的症状并预防猝死。除了预激综合征中的心房颤动外,室上性心律失常因其血流动力学后果而最常接受治疗。频发复杂性室性早搏在某些冠心病患者中可能是抗心律失常治疗的指征,因为这种节律紊乱似乎会增加该情况下的猝死风险。同样,室性早搏对肥厚型心肌病、二尖瓣脱垂和长QT综合征患者的亚组可能具有预后意义。然而,总体而言,所有门诊心律失常患者中只有一小部分需要接受治疗。