Coumel P
Schweiz Med Wochenschr. 1981 Nov 7;111(45):1688-91.
The evaluation of antiarrhythmic drug efficacy can be based on clinical history, ambulatory monitoring and/or clinical electrophysiological investigations. The respective indications for such methods depend mainly on the nature of the arrhythmia, its severity, and the aim of the study. In benign arrhythmias the goal is to improve the patient's symptoms. In chronic arrhythmias Holter monitoring is the best means of quantitating the actual benefit of the treatment. In triggerable paroxysmal arrhythmias electrophysiological methods are very useful even though they do not afford total security as far as long-term follow-up is concerned.
抗心律失常药物疗效的评估可基于临床病史、动态监测和/或临床电生理检查。这些方法各自的适用情况主要取决于心律失常的性质、严重程度以及研究目的。对于良性心律失常，目标是改善患者症状。对于慢性心律失常，动态心电图监测是量化治疗实际获益的最佳方法。对于可诱发的阵发性心律失常，电生理方法非常有用，尽管就长期随访而言，它们并不能提供完全的安全性保障。
