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无临床哮喘的变应性支气管肺真菌病

Allergic bronchopulmonary fungal disease without clinical asthma.

作者信息

Glancy J J, Elder J L, McAleer R

出版信息

Thorax. 1981 May;36(5):345-9. doi: 10.1136/thx.36.5.345.

DOI:10.1136/thx.36.5.345
PMID:7314002
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC471507/
Abstract

During a retrospective survey of patients with pulmonary shadows and blood eosinophilia between the years 1965 and 1980, 42 patients were found with allergic bronchopulmonary fungal disease. Eleven of these had no clinical evidence of asthma. Three of these 11 had hypersensitivity to fungi other than Aspergillus sp. In the absence of asthma there was some difficulty in making a diagnosis, particularly where collapse of the upper lobe occurred in middle-aged or elderly patients and bronchogenic carcinoma was presumed responsible. We suggest that the term allergic bronchopulmonary aspergillosis be replaced by allergic bronchopulmonary fungal disease, the diagnosis be considered in patients with lung disease and blood eosinophilia even in the absence of asthma, and a wider range of fungal allergens be used for skin and precipitin tests.

摘要

在对1965年至1980年间肺部有阴影且血液嗜酸性粒细胞增多的患者进行回顾性调查时,发现42例患有变应性支气管肺真菌病。其中11例无哮喘的临床证据。这11例中有3例对曲霉属以外的真菌过敏。在没有哮喘的情况下,诊断存在一些困难,特别是在中年或老年患者出现上叶肺不张且推测为支气管源性癌的情况下。我们建议将变应性支气管肺曲霉病这一术语替换为变应性支气管肺真菌病,即使在没有哮喘的情况下,对于患有肺部疾病和血液嗜酸性粒细胞增多的患者也应考虑进行诊断,并且应使用更广泛的真菌变应原进行皮肤和沉淀素试验。

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本文引用的文献

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Bronchopulmonary helminthosporiosis.支气管肺链格孢菌病
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