Slavin R G
Postgrad Med. 1976 Apr;59(4):137-41. doi: 10.1080/00325481.1976.11714331.
Early recognition and treatment of immunologically mediated diseases of the lung are vital to prevent irreparable damage. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis are often confused but should not be difficult to distinguish. The former is nonatopic and is marked by chills, fever, chest pains, cough, dyspnea, and restrictive pulmonary function. The immunologic hallmark is the presence of precipitating antibody to the suspected antigen. Allergic bronchopulmonary aspergillosis is atopic and is marked by low-grade fever, obstructive pulmonary function, markedly elevated serum IgE levels, and positive immediate and late response on skin tests. Both diseases respond well to early corticosteroid therapy. Prophylactic measures are also important in controlling extrinsic allergic alveolitis.
早期识别和治疗肺部免疫介导性疾病对于预防不可修复的损害至关重要。外源性过敏性肺泡炎和变应性支气管肺曲霉菌病常被混淆，但不应难以区分。前者是非特应性的，其特征为寒战、发热、胸痛、咳嗽、呼吸困难和限制性肺功能。免疫学标志是存在针对可疑抗原的沉淀抗体。变应性支气管肺曲霉菌病是特应性的，其特征为低热、阻塞性肺功能、血清IgE水平显著升高以及皮肤试验即刻和延迟反应阳性。两种疾病对早期皮质类固醇治疗反应良好。预防措施在控制外源性过敏性肺泡炎方面也很重要。
