Lockner D, Paul C, Hedlund B, Schulman S, Nyman D
Thromb Haemost. 1981 Oct;46(3):652-4.
161 consecutively admitted medical patients with the clinical suspicion of acute deep venous thrombosis (DVT) were thermographed and phlebographed in order to study the congruence of these methods. The sensitivity of thermography in the detection of DVT was found to be 99%, whereas the specificity was only 49%. The low specificity is explained by the fact that all thermographs suggestive of DVT were classified as pathologic to keep the sensitivity of the method as high as possible. Patients with dilated veins which may closely resemble DVT on thermography may in these cases give false positive results. Of 76 patients with phlebographically verified DVT, 22% became thermographically normal within 22 days, whereas 78% did not normalize within the mean observation time of 31 days. In another part of the study all medical patients (101) who were residing in our wards during a period of a week were screened by means of thermography. From this unselected group 17 patients were found to have thermographs suggestive of DVT. In 5 of these patients no reason for pathological thermography could be found. Thermography is a cheap and highly sensitive screening method for DVT, but findings of false positives caused by older thromboses and dilated veins are not unusual. The frequency of such false positives may be minimized by performing thermography after exercise.
为研究这些方法的一致性,对161例临床怀疑急性深静脉血栓形成(DVT)的连续收治内科患者进行了热成像检查和静脉造影。结果发现,热成像检测DVT的敏感性为99%,而特异性仅为49%。特异性低的原因是,为使该方法的敏感性尽可能高,所有提示DVT的热成像图均被归类为病理性。静脉扩张的患者在热成像图上可能与DVT极为相似,在这些情况下可能会给出假阳性结果。在76例经静脉造影证实为DVT的患者中,22%在22天内热成像恢复正常,而在平均31天的观察期内,78%未恢复正常。在该研究的另一部分,对一周内住在我们病房的所有内科患者(101例)进行了热成像筛查。在这个未经过筛选的群体中,发现17例患者的热成像图提示DVT。在其中5例患者中,未发现病理性热成像的原因。热成像是一种用于DVT的廉价且高度敏感的筛查方法,但由陈旧性血栓和静脉扩张导致的假阳性结果并不罕见。通过在运动后进行热成像检查,可将此类假阳性的发生率降至最低。