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与早产儿呼吸窘迫综合征的发病率及重要性相关的产科和新生儿学方面(作者译)

[Obstetric and neonatological aspects relating to incidence and importance of respiratory distress syndrome in prematurely born infants (author's transl)].

作者信息

Müller K, Tiller R

出版信息

Zentralbl Gynakol. 1981;103(18):1070-80.

PMID:7315007
Abstract

Morbidity and mortality due to respiratory distress syndrome (RDS) were analysed for 225 infants prematurely born between the 28th and 36th weeks of pregnancy in 1978. RDS morbidity accounted for 40 per cent, when based on enlarged clinical diagnosis, and for twelve per cent, when based only on radiographic thorax findings of phases II, III, and IV, according to Giedeon, and on histological post-mortem findings from the lungs. Early RDS mortality was found to be 7.5 per cent.--The rates of severe membrane syndromes and early deaths due to RDS were statistically reduced only in one pregnancy group, that is between the 31st and 32nd weeks, following prenatal Prednisolut prophylaxis. No death of infants occurred beyond the 33rd week of pregnancy, and no severe case of RDS was any longer recorded beyond the 34th week. Infants delivered by caesarean section were much more strongly exposed than others to hypoxia. Therefore, no valid information could be established about the impact of caesarean section on the development of RDS.--Conclusions are drawn from the above findings as to obstetric approach to imminent premature birth or to planned premature delivery.

摘要

对1978年28至36周早产的225例婴儿的呼吸窘迫综合征(RDS)发病率和死亡率进行了分析。根据吉迪恩的标准,基于扩大的临床诊断,RDS发病率为40%;若仅基于胸部X线片II、III和IV期表现以及肺部组织学尸检结果,则为12%。早期RDS死亡率为7.5%。——仅在一个孕周组(即31至32周),经产前泼尼松龙预防后,严重膜综合征和RDS所致早期死亡的发生率在统计学上有所降低。妊娠33周后无婴儿死亡,34周后未再记录到严重RDS病例。剖宫产分娩的婴儿比其他婴儿更容易受到缺氧影响。因此,无法确定剖宫产对RDS发生发展的影响。——根据上述发现得出关于即将早产或计划早产的产科处理方法的结论。

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