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关于癌症扩散的喉前连合的形态学研究。

Morphological study of the laryngeal anterior commissure with regard to the spread of cancer.

作者信息

Bagatella F, Bignardi L

出版信息

Acta Otolaryngol. 1981 Jul-Aug;92(1-2):167-71. doi: 10.3109/00016488109133252.

Abstract

This morphological study, done on larynges from male cadavers from 40 to 60 years of age, sectioned horizontally and dye-stained, shows that in the anterior commissure, at the level of the upper surface of the vocal cords, there is a structure which could be of cancerological interest, termed the X-space by the authors. This structure, 1.5-2.0 mm long, is composed of a homogeneous layer of dense fibrous connective tissue located between the dihedral angle of the thyroid cartilage and the laryngeal mucosa. Vascular and glandular formations penetrate the segments above and below this point, making the connective layer less homogeneous. As the X-space is a point of greater resistance to the deep spread of the tumor, the dissemination of cancer at this level is more likely to occur along the mucosa: this allows the surgeon to ascertain the exact margins of the tumor.

摘要

这项形态学研究以40至60岁男性尸体的喉部为对象,进行水平切片和染色处理。研究表明,在声带上面水平的前联合处,存在一种可能具有肿瘤学意义的结构,作者将其称为X间隙。该结构长1.5 - 2.0毫米,由位于甲状软骨二面角与喉黏膜之间的一层均匀致密纤维结缔组织构成。血管和腺性结构贯穿该点上下的节段,使结缔组织层的均匀性降低。由于X间隙是肿瘤深部扩散的阻力较大之处,该水平的癌症扩散更可能沿黏膜发生:这使外科医生能够确定肿瘤的确切边界。

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