正常人类甲状旁腺中的实质细胞团。

The parenchymal cell mass in normal human parathyroid glands.

作者信息

Akerström G, Grimelius L, Johansson H, Lundqvist H, Pertoft H, Bergström R

出版信息

Acta Pathol Microbiol Scand A. 1981 Sep;89(5):367-75. doi: 10.1111/j.1699-0463.1981.tb00234.x.

DOI:10.1111/j.1699-0463.1981.tb00234.x

Abstract

The parenchymal cell mass in parathyroid glands from 368 autopsy cases without apparent parathyroid or kidney disease was investigated. By measuring the glandular density with a density gradient technique and the glandular weight, the parenchymal to fat cell ratio and the weight of the parenchymal cell mass could be determined. The mean parathyroid parenchymal cell weight was calculated to be 22 mg and the maximal normal parenchymal cell weight 39 mg. The glandular weight was evidently dependent on the body constitution, as the fat tissue content of the glands was related to the amount of fat tissue in the body as a whole. The parenchymal cell weight was much less variable. Also, the amount of fat tissue in the parathyroid glands was positively correlated to the size of glands. Thus, the amount of fat cells within parathyroid glands seems less adequate as a histological criterion and the parenchymal cell weight should be of greater value in the histological diagnosis that the weight of the whole gland. The age-and-sex-related variations of the parenchymal cell mass were slight and therefore a value of 39 mg may be considered an appropriate upper limit of the weight of this mass in parathyroid glands of adult persons.

摘要

对368例无明显甲状旁腺或肾脏疾病的尸检病例的甲状旁腺实质细胞团进行了研究。通过用密度梯度技术测量腺体密度和腺体重量，可以确定实质细胞与脂肪细胞的比例以及实质细胞团的重量。计算得出甲状旁腺实质细胞的平均重量为22毫克，正常实质细胞的最大重量为39毫克。腺体重量明显取决于身体构成，因为腺体中的脂肪组织含量与整个身体的脂肪组织量相关。实质细胞重量的变化要小得多。此外，甲状旁腺中的脂肪组织量与腺体大小呈正相关。因此，甲状旁腺内脂肪细胞的数量作为组织学标准似乎不太合适，在组织学诊断中，实质细胞重量可能比整个腺体的重量更有价值。实质细胞团的年龄和性别相关变化很小，因此39毫克的值可被视为成年人甲状旁腺中该细胞团重量的适当上限。