Bayguinov O, Atanassova E
Acta Physiol Pharmacol Bulg. 1981;7(1):3-10.
The electrical activity of the smooth-muscle cells of the intact fundus led off intracellularly by glass microelectrodes with a resistance of 30 to 50 M omega was characterized by slow sinusoidal waves with a frequency of 1 to 2 cpm and an amplitude of 5 to 8 mV. They preceded low-amplitude contractile waves. The membrane potential was 29 +/- 9.83 mV. The resection of 2/3 of the stomach resulted in an increase of the frequency of slow waves--about 4 cpm and of their amplitude--from 12 to 25 mV. The membrane potential became 41.25 +/- 10.59 mV. The slow waves of the fundus after resection had the shape of action potentials type plateau. The contractile waves had a high amplitude and occurred in the same rhythm. The smooth-muscle cells of the intact fundus responded to transmural stimulation mainly with a hyperpolarization, while the smooth-muscle cells of the fundus after resection of the stomach--with depolarization and contraction of the muscle strip. It is concluded that the functional loading leads to deep changes in the pattern of the electrical and contractile activities of the gastric remnant.
用电阻为30至50兆欧的玻璃微电极从完整胃底的平滑肌细胞内引出的电活动，其特征为频率为1至2次/分钟、振幅为5至8毫伏的缓慢正弦波。它们先于低振幅收缩波出现。膜电位为29±9.83毫伏。切除2/3的胃后，慢波频率增加至约4次/分钟，其振幅从12毫伏增加至25毫伏。膜电位变为41.25±10.59毫伏。切除后胃底的慢波呈平台型动作电位形状。收缩波振幅高且以相同节律出现。完整胃底的平滑肌细胞对跨壁刺激主要表现为超极化反应，而胃切除后的胃底平滑肌细胞则表现为去极化和肌条收缩。得出的结论是，功能负荷导致胃残余部分的电活动和收缩活动模式发生深刻变化。
