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[胃体和胃窦部切除术后胃底部平滑肌细胞特性的变化]

[Changes in the properties of smooth muscle cells of the fundus portion of the stomach after removal of the body and antral portion].

作者信息

Baĭginov O, Atanasova E

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Dec;71(12):1615-20.

PMID:4092780
Abstract

Sucrose-gap and microelectrode techniques revealed that the spatial constant (value of electrotonic spread of the slow potential) was greater in fundal portion of stomach with removed body and antral portion than in intact stomach. This finding suggests an increased conductivity of the fundal portion muscle tissue after removal of evacuatory and hormone--producing portions of the stomach. The sodium--calcium nature of the slow potential was revealed in the membrane of fundal smooth muscle cells. After removal of the stomach body and antral portion the permeability of smooth muscle cells is altered in the stomach fundus and the slow potential becomes the same as in the stomach wall of intact dogs. This mechanism of electrophysiological alteration maintains the evacuatory function after removal of the stomach body and antral portion.

摘要

蔗糖间隙法和微电极技术显示,切除胃体和胃窦部后的胃底部,其空间常数(慢电位电紧张性扩布值)比完整胃的更大。这一发现表明,切除胃的排空和激素分泌部分后,胃底部肌肉组织的传导性增加。在胃底部平滑肌细胞膜上发现了慢电位的钠 - 钙特性。切除胃体和胃窦部后,胃底部平滑肌细胞的通透性发生改变,慢电位变得与完整犬的胃壁相同。这种电生理改变机制在切除胃体和胃窦部后维持了排空功能。

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Fiziol Zh SSSR Im I M Sechenova. 1985 Dec;71(12):1615-20.
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