Clements I P, Strelow D A, Becker G P, Vlietstra R E, Brown M L
Am Heart J. 1981 Dec;102(6 Pt 1):980-3. doi: 10.1016/0002-8703(81)90480-4.
A new application of clinical blood pool imaging is described for measurements of limb venous volume and blood flow. Forearm count rate changes determined using blood pool imaging of in vivo Tc-99m labelled red blood cell (RBC) were compared in the same limb to forearm volume changes measured by Whitney mercury-in-silicone rubber strain gauge in eight normal subjects. Intravascular count rate changes closely correlated with volume changes following sudden (mean r = 0.98) and stepwise (mean r = 0.96) limb venous congestion for assessment of venous compliance, as well as for measurement of limb blood flow up to 20 ml/min/100 ml (r = 0.95). These results indicate the accuracy and utility of the radionuclide technique in the study of peripheral circulatory dynamics in clinical settings. In addition, limb tissue fluid accumultion may also be quantified by simultaneous use of radionuclide-strain gauge plethysmography.
本文描述了临床血池成像的一种新应用，用于测量肢体静脉容量和血流。在八名正常受试者中，将使用体内 Tc-99m 标记红细胞（RBC）血池成像测定的前臂计数率变化，与同一肢体中通过惠特尼汞-硅橡胶应变仪测量的前臂容量变化进行比较。在评估静脉顺应性以及测量高达 20 ml/min/100 ml 的肢体血流时（r = 0.95），血管内计数率变化与突然（平均 r = 0.98）和逐步（平均 r = 0.96）肢体静脉充血后的容量变化密切相关。这些结果表明放射性核素技术在临床环境中研究外周循环动力学方面的准确性和实用性。此外，同时使用放射性核素-应变仪体积描记法也可以对肢体组织液积聚进行量化。
