Gerber J E, Casey C A, Martin P, Winn W C
Am J Clin Pathol. 1981 Dec;76(6):816-8. doi: 10.1093/ajcp/76.6.816.
One hundred four autopsy cases with previously diagnosed pneumonitis were examined for evidence of Legionnaires' disease. The peak epidemic months of July, August, and September in the five years before the 1977 Vermont epidemic were chosen for study. The bacterium, Legionella pneumophila (serogroup 1) was demonstrated in lung tissue by direct immunofluorescence and the Dieterle silver impregnation stain. There was no clustering of Legionnaires' disease in any one year., The clinical presentation and pulmonary pathology were similar to that of Legionnaires' disease previously reported in Vermont. Seven out of 104 cases were identified as previously undiagnosed Legionnaire's disease. In this time frame, it can be concluded that the disease has been endemic in Vermont.
对104例先前诊断为肺炎的尸检病例进行了检查,以寻找军团病的证据。选择了1977年佛蒙特州疫情前五年中7月、8月和9月这几个疫情高峰月进行研究。通过直接免疫荧光法和迪特尔勒银浸染染色法在肺组织中证实了嗜肺军团菌(血清群1)。军团病在任何一年都没有聚集现象。临床表现和肺部病理学与佛蒙特州先前报告的军团病相似。104例病例中有7例被确定为先前未诊断出的军团病。在这个时间段内,可以得出结论,该病在佛蒙特州一直呈地方性流行。