Richards W, Azen S P, Weiss J, Stocking S, Church J
Ann Allergy. 1981 Nov;47(5 Pt 1):348-54.
Indices of air pollution, meteorological conditions and airborne allergens were correlated with emergency room census and hospitalizations for asthma at the Childrens Hospital of Los Angeles (CHLA) during a six-month period encompassing high and low periods of air pollution. In addition, patients in residence at the Sunair Home for Asthmatic Children (SHAC) were studied during a 10-day peak air pollution period. Increases in asthma emergency room visits and hospitalizations correlated significantly with increases in nitric oxide, coefficient of haze, hydrocarbons, Santa Ana wind conditions and total airborne allergen counts. Significant correlations were also found with decreases in ambient levels of O3, SO2, temperature and relative humidity. Among SHAC patients morning peak flow levels were significantly lower during the 10-day peak pollution period than during two control periods of low pollution. However, neither differences in clinical symptoms experienced by these patients nor their need for additional medication were observed.
在洛杉矶儿童医院(CHLA)为期六个月的空气污染高峰期和低谷期,空气污染指数、气象条件和空气中的过敏原与哮喘急诊室就诊人数及住院人数相关。此外,在空气污染高峰期的10天内,对哮喘儿童阳光之家(SHAC)的住院患者进行了研究。哮喘急诊室就诊人数和住院人数的增加与一氧化氮、雾霾系数、碳氢化合物、圣安娜风况以及空气中过敏原总数的增加显著相关。同时也发现,臭氧、二氧化硫、温度和相对湿度的环境水平降低也存在显著相关性。在SHAC患者中,10天的污染高峰期早晨的峰值流量水平显著低于两个低污染对照期。然而,这些患者的临床症状或额外用药需求均未出现差异。