Huacuja L, Delgado N M, Calzada L, Wens A, Reyes R, Pedrón N, Rosado A
Arch Androl. 1981 Dec;7(4):343-9. doi: 10.3109/01485018108999329.
Normal and pathological semen were studied with regard to cholesterol and phospholipid content of sperm cells and seminal plasma. Spermatozoa from pathologic semen have similar concentrations of phospholipid-phosphorous and significantly higher cholesterol concentration than spermatozoa from normal semen. However, only oligoasthenospermic spermatozoa showed a significantly higher cholesterol/phospholipid ratio. Azoospermic seminal plasma showed the lowest values of both cholesterol and phospholipids, but the ratio of cholesterol to phospholipids was equal to that in normal spermatozoa. No significant difference was found in the cholesterol concentration of seminal plasma from oligoasthenospermic, asthenospermic, and normospermic subjects and only asthenospermic plasma showed a significantly lower concentration of this compound. Cholesterol and phospholipid exchange between sperm cells and seminal plasma was shown by the striking correlation between the lipid composition of seminal plasma with that of sperm cells.
对正常和病理状态下的精液进行了研究，分析精子细胞和精浆中的胆固醇及磷脂含量。病理性精液中的精子，其磷脂磷浓度与正常精液中的精子相似，但胆固醇浓度显著更高。然而，只有少弱精子症患者的精子胆固醇/磷脂比值显著更高。无精子症患者的精浆中胆固醇和磷脂含量均最低，但胆固醇与磷脂的比值与正常精子中的该比值相等。少弱精子症、弱精子症和正常精子症患者精浆中的胆固醇浓度无显著差异，只有弱精子症患者的精浆中该化合物浓度显著更低。精子细胞与精浆之间的胆固醇和磷脂交换表现为精浆与精子细胞的脂质组成之间存在显著相关性。
