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[酒精性肝硬化患者的血清假性胆碱酯酶水平。与解剖功能损害程度的相关性。不良预后指标]

[Serum levels of pseudocholinesterase in alcoholic cirrhosis patients. Correlation with the extent of anatomo-functional damage. Unfavorable prognostic index].

作者信息

Sportiello V, Pace M, Fernandes D, Stefan C

出版信息

Arch Sci Med (Torino). 1981 Jul-Sep;138(3):307-13.

PMID:7316740
Abstract

Following an introduction on the question of pseudocholinesterase (CHE) in cirrhosis of the liver and acute and chronic hepatopathy, a personal study of 35 chronic cases at various stages of the disease is reported. The patients were submitted to the usual haematochemical liver function tests as well as to liver needle biopsy with anatomo-functional staging of the liver trouble, which was largely due to alcohol poisoning. The CHE level in these patients was monitored until death. On the basis of the results, measurement of CHE is identified as an index not only of liver function (this is of course well known) but of prognosis infausta, there being a confirmed correlation between survival and CHE serum level.

摘要

在介绍了肝脏 cirrhosis、急慢性肝病中假性胆碱酯酶(CHE)的问题之后,报告了对 35 例处于疾病不同阶段的慢性病例的个人研究。这些患者接受了常规的血液化学肝功能检查以及肝脏穿刺活检,并对肝脏病变进行了解剖功能分期,该病变主要是由酒精中毒引起的。对这些患者的 CHE 水平进行监测直至死亡。根据结果,CHE 的测量不仅被确定为肝功能指标(这当然是众所周知的),而且是不良预后的指标,生存与血清 CHE 水平之间存在确定的相关性。

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