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[给正常动物和实验性高胆固醇血症动物经肠胃外注射体内获取的异种脑脊液后微循环床血管的变化]

[Changes in vessels of the microcirculatory bed following parenteral administration of xenogeneic cerebrospinal fluid obtained in vivo to normal animals and animals with experimental hypercholesterolemia].

作者信息

Tkach V V, Ziablov V I, Zadniprianyĭ I V, Sivukha N I, Vinogradov S A

出版信息

Arkh Anat Gistol Embriol. 1981 Sep;81(9):60-6.

PMID:7316805
Abstract

Effect of parenteral administration of xenogenic liquor, vitally obtained, on the state of the microcirculatory bed, as well as its biostimulating action for cellular metabolism activation have been studied. The number of actively functioning capillaries increases, microvessels dilate, vascular permeability intensifies not only under normal conditions, but under experimental hypercholesteremia, as well. How the changes observed in the microcirculatory bed depend on various doses and total amount of the preparation administered, as well as means of its conservation have been analysed and stated. The dynamics of indices on lipid metabolism have been studied.

摘要

研究了经静脉注射新鲜获取的异种液体对微循环床状态的影响及其对细胞代谢激活的生物刺激作用。不仅在正常条件下,而且在实验性高胆固醇血症条件下,功能活跃的毛细血管数量增加、微血管扩张、血管通透性增强。分析并阐述了微循环床中观察到的变化如何取决于所给药制剂的不同剂量和总量以及其保存方式。还研究了脂质代谢指标的动态变化。

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