Fisher J R, Sievers M L, Takeshita R T, Caldwell H
Ariz Med. 1981 Nov;38(11):833-5.
A woman with chronic pyelonephritis developed progressive muscular weakness and bone pain. For twenty years she had habitually ingested fluoride-rich soil. Osteosclerosis was found on x-ray examination, and fluorosis was confirmed by bone biopsy. Renal failure augmented skeletal retention of excessive fluoride intake which, in turn, appears to have intensified symptomatic renal osteodystrophy. Skeletal fluorosis from this unexpected source has not been previously described.
一名患有慢性肾盂肾炎的女性出现了进行性肌肉无力和骨痛。二十年来,她一直有习惯性摄入富含氟化物土壤的行为。X线检查发现骨硬化,骨活检证实为氟中毒。肾衰竭增加了骨骼对过量氟摄入的潴留,而这反过来似乎又加剧了有症状的肾性骨营养不良。这种意想不到来源导致的骨氟中毒此前尚未有过描述。