Ibrahim A L, Chulan U, Babjee A M
Aust Vet J. 1981 Jun;57(6):277-80. doi: 10.1111/j.1751-0813.1981.tb05813.x.
An Australian strain of Newcastle disease virus, was evaluated for used as a vaccine following its administration by drinking water, aerosol and spray to chickens at 1 and 21 days of age. Haemagglutination inhibition antibody was produced and persisted for 11 weeks. Aerosol vaccination induced higher levels of haemagglutination inhibition antibody than the other methods of vaccination. No respiratory disease was observed following vaccination. Chickens vaccinated by aerosol and spray were fully protected when challenged at 5, 7 and 11 weeks of age with virulent Newcastle disease virus. Mortality of 10 to 30 per cent was observed in chickens vaccinated by drinking water and intranasally following challenge.
对一种澳大利亚株新城疫病毒进行了评估，在1日龄和21日龄的鸡通过饮水、气溶胶和喷雾方式接种后用作疫苗。产生了血凝抑制抗体并持续了11周。气溶胶接种诱导产生的血凝抑制抗体水平高于其他接种方法。接种后未观察到呼吸道疾病。在5、7和11周龄时用强毒新城疫病毒攻毒时，通过气溶胶和喷雾接种的鸡得到了完全保护。饮水和滴鼻接种的鸡在攻毒后观察到10%至30%的死亡率。
